Is Atorvastatin Cheaper Than Simvastatin
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Atorvastatin is used to treat high cholesterol. Atorvastatin is also used to lower the risk of stroke, heart attack, or other heart complications in people with coronary heart disease or type 2 diabetes. Atorvastatin is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body. Atorvastatin reduces low-density lipoprotein (LDL) cholesterol and total cholesterol in the blood. Lowering your cholesterol can help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease.
Generic atorvastatin by mylan, while at least 2 more on the market had "atorvastatin", "teror" or similar prefix. The first thing to note is that atorvastatin has to be dissolved before it can used as intravenous therapy in patients <18 years of age. Atorvastatin is sold in tablet form as a 300 mg tablet, and by the gram as in generic form, where 300 mg is about half of 3 mg. The other drug with same effect is digoxin, a potassium-sparing diuretic (such as furosemide) with the common name of dextrose. Unlike atorvastatin, dextrose is not available as a product that is dissolved in water before or right after use. Even for those who are at risk for hyperkalemia, which many Americans could be today, the cost of a dose atorvastatin at the usual per day will probably not be sufficient to make it a significant portion of their usual cholesterol dosage.
In contrast, the cost is generally low and consistent with the price of any oral medication, and as a matter of medical practice it is typically recommended that patients with high cardiovascular risk follow a statin, such as lovastatin or simvastatin, instead of atorvastatin. As 2008, Online viagra is it real
the price of lovastatin, at usual dose per day, ranged between $60 and $70 for a one-tablet-per-day dose. At $75 and $90/month, which are reasonable estimates based on a person making $50,000 year, this translates into the cost of a dose lovastatin as high $350 at the usual dose, or $180 for the lower dose range of 80 to 240 mg per day. Simvastatins are available at very similar prices and have less adverse reactions.
So just where are the potential harms? primary risk is not from atorvastatin but its metabolite, drostanolone acetate. This drug, which is cheapest atorvastatin also called stanozolol (delta-9-hydroxybutyrate), at all doses, has shown a small increase in lipids and total cholesterol adults with metabolic syndrome. Even more surprisingly, the effects for patients with cardiovascular disease was smaller, and generally not statistically significant. But there is not a single safety trial, either postmarketing or prior to 2005 (when the FDA first authorized atorvastatin for use in patients with heart failure from atorvastatina generico precio
1998 at a maximum dose of 500 mg per day) that has shown any problems associated with the use of atorvastatin or its metabolite. Moreover, one reason that the dose would need to be very high raise the risk of this effect is because the risk would only appear in patients with metabolic syndrome.
But that is not to say the drug or its metabolite don't pose any risk in drug-naive patient. At the extreme, drug can raise liver enzymes, especially when taken with other drugs that can cause hepatic injury (methotrexate). However, most patients probably don't develop any effect precio atorvastatina generico
more severe than similar patients on non-steroidal anti-inflammatory drugs (such as aspirin) or non-steroidal anti-inflammatory drugs without a hepatic complication (aspirin). Aspirin was also approved in the 1980s at 800 mg/day, a dose that is far higher than for which safety is known and that, at that time, was the usual dose of drug. A small minority patients had serious (i.e., life-threatening) adverse events even at this dose.
The other safety concern is drug's potential to alter normal heart rhythm in some patients. At the very least this can raise risks for patients who have undergone major surgery (including open heart surgery, valve replacement, bypass and the transplantation of myocardial muscle). dose atorvastatin should be lowered in patients with cardiac defects (such as heart transplant) well in patients who have a history of atrioventricular block caused by other cardiotoxic medications. This would avoid the potential problem of cardiac arrest that other atorvastatin doses have caused, for example. Patients with known arrhythmia (including atrial fibrillation or ventricular fibrillation) should receive a lower dose of atorvastatin, based on the degree of cardiac instability.
It is also important to realize that the risk for patients undergoing coronary artery bypass surgery is low, and in some cases may even be beneficial. An estimated 3-4 Atomoxetine generic
million patients in the United States undergo coronary artery bypass surgery each year, and the rate of cardiac arrest has decreased significantly since the time when it was leading cause of death among U.S. patients undergoing such surgery. Nevertheless, it is a common precaution to.
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